Madhulika B Gupta Selected Research

Fetal Growth Retardation (Intrauterine Growth Retardation)

1/2022	Increased Colocalization and Interaction Between Decidual Protein Kinase A and Insulin-like Growth Factor-Binding Protein-1 in Intrauterine Growth Restriction.
10/2021	IGFBP-1 hyperphosphorylation in response to nutrient deprivation is mediated by activation of protein kinase Cα (PKCα).
1/2021	Mechanisms linking hypoxia to phosphorylation of insulin-like growth factor binding protein-1 in baboon fetuses with intrauterine growth restriction and in cell culture.
1/2021	Mechanistic Target of Rapamycin Complex 1 Signaling Links Hypoxia to Increased IGFBP-1 Phosphorylation in Primary Human Decidualized Endometrial Stromal Cells.
1/2021	Mechanistic Target of Rapamycin Complex 2 Regulation of the Primary Human Trophoblast Cell Transcriptome.
1/2020	Hyperphosphorylation of fetal liver IGFBP-1 precedes slowing of fetal growth in nutrient-restricted baboons and may be a mechanism underlying IUGR.
1/2020	mTORC1 Transcriptional Regulation of Ribosome Subunits, Protein Synthesis, and Molecular Transport in Primary Human Trophoblast Cells.
1/2020	Inhibition of decidual IGF-1 signaling in response to hypoxia and leucine deprivation is mediated by mTOR and AAR pathways and increased IGFBP-1 phosphorylation.
1/2020	Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction.
1/2019	IUGR Is Associated With Marked Hyperphosphorylation of Decidual and Maternal Plasma IGFBP-1.

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Madhulika B Gupta Research Topics

Disease

23	Fetal Growth Retardation (Intrauterine Growth Retardation) 01/2022 - 01/2009
12	Hypoxia (Hypoxemia) 01/2022 - 01/2009
4	Placental Insufficiency 01/2019 - 01/2016
2	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 01/2018
2	Tuberous Sclerosis (Bourneville's Disease) 01/2021 - 02/2016
1	Malnutrition (Nutritional Deficiencies) 01/2021
1	Inflammation (Inflammations) 01/2021
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2018
1	Neural Tube Defects (Exencephaly) 01/2018
1	Pregnancy Complications 01/2016
1	Fetal Hypoxia 01/2016
1	Birth Weight (Birth Weights) 04/2010
1	Neoplasms (Cancer) 08/2007

Drug/Important Bio-Agent (IBA)

13	Insulin-Like Growth Factor Binding Protein 1IBA 01/2022 - 01/2009
7	Insulin-Like PeptidesIBA 01/2022 - 01/2009
7	Insulin-Like Growth Factor I (IGF-1)IBA 10/2021 - 01/2009
7	Proteins (Proteins, Gene)FDA Link 01/2021 - 04/2011
6	Sirolimus (Rapamycin)FDA Link 01/2021 - 02/2016
6	Leucine (L-Leucine)FDA Link 01/2020 - 01/2009
5	Mechanistic Target of Rapamycin Complex 1IBA 01/2021 - 02/2016
5	Amino Acids FDA Link 01/2020 - 12/2015
4	Insulin-Like Growth Factor Binding ProteinsIBA 10/2021 - 01/2009
4	Oxygen (Dioxygen)IBA 01/2021 - 02/2016
3	Insulin (Novolin)FDA Link 01/2022 - 01/2018
3	Small Interfering RNA (siRNA)IBA 01/2021 - 02/2016
3	Mechanistic Target of Rapamycin Complex 2IBA 01/2021 - 02/2016
2	Casein Kinase II (Casein Kinase 2)IBA 01/2020 - 04/2014
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2022
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 10/2021
1	EchinomycinIBA 01/2021
1	LeptinIBA 01/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2021
1	MicronutrientsIBA 01/2021
1	ribosomal protein S10IBA 01/2020
1	Ribosomal Proteins (Ribosomal Protein)IBA 01/2020
1	Casein Kinases (Casein Kinase)IBA 01/2020
1	Biomarkers (Surrogate Marker)IBA 01/2019
1	Folic Acid TransportersIBA 01/2018
1	Perilipin-2IBA 01/2018
1	Caseins (Casein)FDA Link 01/2018
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2018
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2018
1	IsotopesIBA 01/2018
1	LipidsIBA 01/2018
1	IGF Type 1 Receptor (IGF 1 Receptor)IBA 02/2016
1	MTOR InhibitorsIBA 02/2016
1	1-(2-(dodecyloxy)ethyl)pyrrolidine hydrochloride (DEP)IBA 02/2016
1	Plasminogen Activator Inhibitor 1IBA 01/2016
1	Indicators and Reagents (Reagents)IBA 01/2016
1	GlucocorticoidsIBA 08/2013
1	PhosphoenolpyruvateIBA 08/2013
1	Angiogenic ProteinsIBA 04/2011
1	Serine (L-Serine)FDA Link 04/2010
1	Biological ProductsIBA 01/2009
1	Protein Isoforms (Isoforms)IBA 01/2009
1	Hormones (Hormone)IBA 08/2007

Therapy/Procedure

2	Ligation 01/2020 - 01/2018